DISCLAIMER: The tools, as they currently stand, are provided for research and informational purposes only. The underlying models, assumptions, data sources, and methodologies are experimental and might have not yet been peer-reviewed or independently validated. Outputs may be incomplete, uncertain, or inaccurate and should be interpreted with caution. The tools do not provide regulatory, medical, legal, toxicological, or professional risk assessment advice. For the time being, it must not be used as a substitute for expert judgment, regulatory review, or established risk-assessment frameworks, nor relied upon for decision-making related to human health, environmental protection, occupational safety, product registration, compliance, or policy.
Use of these tools for unlawful, harmful, misleading, or unethical purposes—including but not limited to regulatory circumvention, misrepresentation of risk, or inappropriate application to real-world pesticide use decisions—is strictly prohibited. The tool is provided “as is,” without warranties of any kind, express or implied, including but not limited to accuracy, fitness for a particular purpose, or non-infringement.
Toxicity / Ecotoxicity – Introduction
The tools in this section provide an overview of the main outcomes from the toxicity and ecotoxicity tests conducted within the SPRINT project. They allow users to explore and compare toxicity and ecotoxicity results, understand methodological approaches, and assess how mixtures of concern may impact both human (toxicity) and environmental (ecotoxicity) health.
In Toxicity results, the findings on the effects of pesticide and their mixtures at doses that are considered safe are presented. Starting from previous biomonitoring, and following a scientific process through three consecutive phases (Tiers), the top pesticides of concern were selected and tested till the final phase of the tiered approach. Single pesticides and their mixtures were tested in silico, in vitro, and in vivo, and the results are presented separately for these Tiers, indicating where significant toxic effects were observed. These findings support the effectiveness of a component-based approach for assessing the risks of pesticide mixtures.
In Ecotoxicity results, the findings from laboratory-based ecotoxicity assessments are presented, focusing on the effects of pesticide mixtures on non-target organisms from terrestrial (soil) and aquatic (water) compartments. In the introduction, the approach for mixture testing and mixture selection is described, while the methodology section shows the procedure followed for the different species tested. The results are presented in graphical form, separated by species, indicating where significant toxic effects were observed.
